Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies


This article used computer modeling to screen for viable galectin antagonists to attach to the spike protein. The same methodology was employed to search for the 3CL protease and RdRp. The results uncovered one compound GB-0139 (TD-139) that looked good and eventually achieved good clinical trial results not discussed in the article. There were a total of 5 compounds that were analyzed for their molecular docking capability.